AN UNBIASED VIEW OF CONOLIDINE

The 1st asymmetric overall synthesis of conolidine was formulated by Micalizio and coworkers in 2011.[two] This artificial route will allow use of possibly enantiomer (mirror image) of conolidine by means of an early enzymatic resolution."We confirmed that conolidine binds on the freshly identified opioid receptor ACKR3, though exhibiting no affini